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Clinical Trials

Clinical Trial Image of a keyboard, pen, stethoscope and heart over a pink background

Patient involvement in clinical trials is crucial to our community. The first ever clinical trial for MOGAD was announced in October of 2021!  As research moving forward, there will be more clinical trials in the near future.

Please Keep checking all trial links as sites are continually being identified

What is a Clinical Trial and how does it work?

Our contacts at Roche/Genentech have generously supplied a great video for you to watch to help you understand what you need to know about clinical trials in general.  Watch the video below for a great overview:

Current Clinical Trials for MOGAD


Sponsored by UCB Biopharma SRL

Learn more about the study from the CosMOG website.

There is also more information and someone to connect to to answer questions and help connect you to specialists at KnowRare.

Watch these videos to help you understand the cosMOG Trial

These two videos provide a great review of what Rozanolixizumab does as well as a friendly discussion with Dr. Michael Levy and two MOGAD patients who are currently in the clinical trial.


Sponsored by Hoffmann-La Roche

Learn more about the study from the Meteoroid website. (source

The infographics below will help you understand the process in this trial courtesy of


While not yet a clinical trial, one of the most exciting areas of research is Tolerization for the MOG antibody.  It is also being looked at for the AQP-4 antibody as well, which is detectable in many NMOSD patients.

The Guthy-Jackson Charitable Foundation has this page on the subject.  We share this with you so that you can watch as this area of research develops:


Pioneer | Curative Therapies


It is hoped that this will trnaslate to clinical trials in the near future.