Clinical Trials
Patient involvement in clinical trials is crucial to our community. The first ever clinical trial for MOGAD was announced in October of 2021! As research moves forward, there will be more clinical trials in the near future.
Read below to learn about a couple of current clinical trials for MOGAD.
Please Keep checking all trial links as sites are continually being identified and updated
Learn about Clinical Trials
What is a clinical trial and how does it work?
The two videos below provide a great overview of clinical trials and highlight current and future trials for MOGAD.
Our contacts at Roche/Genentech have generously supplied a great video to help you understand what you need to know about clinical trials in general. Watch the video above to learn more.
If you are thinking about joining any clinical trial for MOGAD, you really need to watch this discussion between Dr. Michael Levy from the Neuroimmunology Clinic and Research Laboratory at Massachusetts General Hospital and Associate Professor Sudarshini Ramanathan from Concord Hospital, University of Sydney, who teach us about the design and execution of clinical trials and what we as patients can expect when joining a clinical trial for MOGAD.
Dr. John Chen from Mayo Clinic presents this session as part of the US MOGAD Patient Summit 2025 on Understanding Clinical Trials and How They Benefit the MOGAD Communty.
We have created another helpful guide on the basics of Cinical Trials:
Will Tolerization Lead to a Possible Clinical Trial?
While not yet a clinical trial, one of the most exciting areas of research is Tolerization for the MOG antibody. It is also being looked at for the AQP-4 antibody, which is detectable in many NMOSD patients.
The Guthy-Jackson Charitable Foundation has this page on the subject. We share this with you so that you can watch as this area of research develops: Pioneer | Curative Therapies
It is hoped that this will translate to clinical trials in the near future.